3 ms·

I'm not making things up as much as you'd like to sound cute and demeaning. Here are just a few easy to find sources: https://www.ncbi.nlm.nih.gov/pubmed/32205

I'm not making things up as much as you'd like to sound cute and demeaning. Here are just a few easy to find sources: https://www.ncbi.nlm.nih.gov/pubmed/32205204 https://www.ncbi.nlm.nih.gov/pubmed/32205204 https://www.ncbi.nlm.nih.gov/pubmed/32171740 https://www.ncbi.nlm.nih.gov/pubmed/32171740 https://www.ncbi.nlm.nih.gov/pubmed/32373993 https://www.ncbi.nlm.nih.gov/pubmed/32373993

Reelin 6y ago
> as much as you'd like to sound cute and demeaning My intention wasn't to demean but rather to provide a clear and understandable message for other readers who might lack the scientific background to critically evaluate your claims. I was also hoping that you'd take the hint that perhaps you lack the requisite background knowledge to commentate usefully on the topic. The first two links are the ones with unexplainable results (to put it charitably) by the now infamous Dr. Raoult. The third one is a review which identifies previous successes in vitro and argues for further clinical trials to take place. In vitro studies are useful for identifying drug candidates to test but say absolutely nothing about whether something will work in practice. Meanwhile, the link I provided in my previous comment neatly summarizes the current clinical data on the topic. In a nutshell, hydroxychloroquine does not appear to be particularly useful for treating hospitalized patients. It might or might not have some mild beneficial effects and it definitely has serious safety concerns; the arrival of additional clinical trial data in the near future should hopefully give us a more complete picture. I stress again that there are currently no known effective treatments.
- Izkata 6y ago
  > In a nutshell, hydroxychloroquine does not appear to be particularly useful for treating hospitalized patients. The early reports suggested it was only useful in combination with zinc supplements, which seems to have been largely forgotten or ignored, from what I've picked up on in comments and links across multiple sites over the past month or two.
nl 6y ago
Two of those are the discredited French study and the other is a metastudy that includes those findings along with lab results (ie, not actually showing it works in people).

Reelin 6y ago

> as much as you'd like to sound cute and demeaning My intention wasn't to demean but rather to provide a clear and understandable message for other readers who might lack the scientific background to critically evaluate your claims. I was also hoping that you'd take the hint that perhaps you lack the requisite background knowledge to commentate usefully on the topic. The first two links are the ones with unexplainable results (to put it charitably) by the now infamous Dr. Raoult. The third one is a review which identifies previous successes in vitro and argues for further clinical trials to take place. In vitro studies are useful for identifying drug candidates to test but say absolutely nothing about whether something will work in practice. Meanwhile, the link I provided in my previous comment neatly summarizes the current clinical data on the topic. In a nutshell, hydroxychloroquine does not appear to be particularly useful for treating hospitalized patients. It might or might not have some mild beneficial effects and it definitely has serious safety concerns; the arrival of additional clinical trial data in the near future should hopefully give us a more complete picture. I stress again that there are currently no known effective treatments.

Izkata 6y ago
> In a nutshell, hydroxychloroquine does not appear to be particularly useful for treating hospitalized patients. The early reports suggested it was only useful in combination with zinc supplements, which seems to have been largely forgotten or ignored, from what I've picked up on in comments and links across multiple sites over the past month or two.

nl 6y ago

Two of those are the discredited French study and the other is a metastudy that includes those findings along with lab results (ie, not actually showing it works in people).