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I know of at least one study in COVID-19 cases that suggested a correlation between mortality and Vitamin D levels [0], tested in patients rather than comparing

I know of at least one study in COVID-19 cases that suggested a correlation between mortality and Vitamin D levels [0], tested in patients rather than comparing national averages. That said, I'd like to see more tests in confirmed cases and even more than just mortality correlation, I'd like to see if it helps with long term lung damage. [0]: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3585561 https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3585561

atourgates 6y ago
That's really interesting, and has an even stronger conclusion: "When controlling for age, sex, and comorbidity, Vitamin D status is strongly associated with COVID-19 mortality outcome of cases."
- elliekelly 6y ago
  The vitamin D deficiency is particularly interesting to me with respect to pregnant women and smokers. There have been cases of pregnant women who were unknowingly infected with Covid-19[1] and it seems there’s some evidence the smokers are less likely to be admitted to the hospital with a severe case. I would expect both groups to have higher than average vitamin D regardless of their age, background, health issues. Pregnant women consistently take prenatal vitamins for months and (most) smokers consistently get daily sun exposure because they go outside to smoke. And from what little we know it seems both groups fare better when they are infected. [1]https://www.nejm.org/doi/full/10.1056/NEJMc2009316 https://www.nejm.org/doi/full/10.1056/NEJMc2009316
DanBC 6y ago
There's this, which didn't find much: https://www.cebm.net/covid-19/vitamin-d-a-rapid-review-of-the-evidence-for-treatment-or-prevention-in-covid-19/ https://www.cebm.net/covid-19/vitamin-d-a-rapid-review-of-th... > We found no clinical evidence on vitamin D in COVID-19. There was no evidence related to vitamin D deficiency predisposing to COVID-19, nor were there studies of supplementation for preventing or treating COVID-19. > There is some evidence that daily vitamin D3 supplementation over weeks to months may prevent other acute respiratory infections, particularly in people with low or very low vitamin D status. This evidence has limitations, including heterogeneity in study populations, interventions, and definitions of respiratory infections that include upper and lower respiratory tract involvement.

atourgates 6y ago

That's really interesting, and has an even stronger conclusion: "When controlling for age, sex, and comorbidity, Vitamin D status is strongly associated with COVID-19 mortality outcome of cases."

elliekelly 6y ago
The vitamin D deficiency is particularly interesting to me with respect to pregnant women and smokers. There have been cases of pregnant women who were unknowingly infected with Covid-19[1] and it seems there’s some evidence the smokers are less likely to be admitted to the hospital with a severe case. I would expect both groups to have higher than average vitamin D regardless of their age, background, health issues. Pregnant women consistently take prenatal vitamins for months and (most) smokers consistently get daily sun exposure because they go outside to smoke. And from what little we know it seems both groups fare better when they are infected. [1]https://www.nejm.org/doi/full/10.1056/NEJMc2009316 https://www.nejm.org/doi/full/10.1056/NEJMc2009316

DanBC 6y ago

There's this, which didn't find much: https://www.cebm.net/covid-19/vitamin-d-a-rapid-review-of-the-evidence-for-treatment-or-prevention-in-covid-19/ https://www.cebm.net/covid-19/vitamin-d-a-rapid-review-of-th... > We found no clinical evidence on vitamin D in COVID-19. There was no evidence related to vitamin D deficiency predisposing to COVID-19, nor were there studies of supplementation for preventing or treating COVID-19. > There is some evidence that daily vitamin D3 supplementation over weeks to months may prevent other acute respiratory infections, particularly in people with low or very low vitamin D status. This evidence has limitations, including heterogeneity in study populations, interventions, and definitions of respiratory infections that include upper and lower respiratory tract involvement.