3 ms·
> Most of the explosion in aging research (and virtually all the venture capital startups) are looking to treat aging at the cellular level.... The truth, as Ka
by floatrock 6y ago
> Most of the explosion in aging research (and virtually all the venture capital startups) are looking to treat aging at the cellular level.... The truth, as Katcher understands it, is that, to a large extent, aging is coordinated system-wide via signal molecules in the blood.
So the SV execs with their fit young blood-bois were right all along?
- henearkr 6y agoAlso, telomeres shortening is a real thing. So... so much for a signal-only mechanics!
- andreygrehov 6y agoI had the exact same thought. I wonder where those execs get the information from and more importantly, how the information is filtered, because they are clearly a few years ahead of what's being posted on, say, HN.
- maxwell 6y agoIt was widely reported years ago. The future is already here it's just not affordable. I remember talking about recent news that a few of us had heard about promising "young blood rejuvenation" with a bunch of random hicks in the woods of central Maine in the spring of 2014.
- Medicalidiot 6y agoSignaling within the body is a cascade-like phenomenon where every step gets progressively more enhanced. It makes more sense to target upstream events since one can use less to have a stronger response. A classic example of this is nasal steroids for seasonal allergies versus histamine blockers. Steroids will actually cause the genes that code for histamine/inflammatory proteins that are released by the cells to be downregulated. Whereas antihistamines bind to the histamine receptor at the penultimate step in the process. Steroids have a much stronger effect and are the current first line treatment for allergic rhinitis.