4 ms·
1) It's only rat tissues and human tissues; any research published in only tissues only or in ratsonly , and not a large RCT in actual humans, needs to be taken
by WhompingWindows 6y ago
1) It's only rat tissues and human tissues; any research published in only tissues only or in ratsonly , and not a large RCT in actual humans, needs to be taken with a huge grain of salt.
2) The research in the blog post is not fully summarized. You know it's a weak blog post when they post results WITHOUT SAMPLE SIZE. This is a GLARING omission and highly unscientific. The actual paper shows n=593 rat tissues and n=850 human tissues, which is fine but the blog post should report on these details.
3) It's not that new to suggest that younger individuals' blood plasma might have a rejuvenating effect.
4) They look at certain tissue types, which wouldn't result in changes to all tissue types, like skin, hair, brain, etc.
5) This is very early stages, again, we need actual trials in humans, and then those trials probably need to be followed up for years and years, since aging is a long-run phenomenon. This is more like a cohort study where we enroll a huge number into a cohort of aging-treatments and controls who have some other placebo-treatment.
- pmiller2 6y agoThis sounds to me like a very strong pilot study: something that's very likely to attract additional grant funding, but may or may not pan out in the real world.
- tropheusduboisi 6y agoSome of the figures are based on N=6 treated old rats.