4 ms·
Yes, it's entire possible that the "cytokine storm" hypothesis turns out to be wrong. Here's my inexpert summary of what some researchers believe: A buildup of
by richij 6y ago
Yes, it's entire possible that the "cytokine storm" hypothesis turns out to be wrong. Here's my inexpert summary of what some researchers believe: A buildup of superoxide radicals leads to a buildup of other "reactive oxygen species," all of which cause acute oxidative stress—notably in the endothelia.
So COVID-19 attacks the endothelial structures throughout the body. Notably the interface between lungs and blood vessels, but also the heart, other vital organs, capillaries, etc. Hence clotting and "sticky blood" is a huge problem.
Unsurprisingly, bad diet messes up one of the pathways the body uses to cleans up superoxide radicals—chronic high sugar and lack of trace elements (zinc, copper, magnesium). And now it seems C19 messes up another pathway, thanks to it interfering with ACE2 receptors. This could be why we're seeing high mortality in people with diabetes, pre-diabetes, and all the other conditions related to poor blood-sugar regulation—obesity, coronary artery disease, dementia, etc.
A good summary at: https://www.youtube.com/watch?v=Aj2vB_VITXQ https://www.youtube.com/watch?v=Aj2vB_VITXQ
- rpiguy 6y agoVitamin D appears to be playing a large role as well. I wondered why France wasn't hit harder and all I could come up with was wine (antioxidant) and cheese (vitamin D from dairy). India is another country that follows this pattern tumeric (antioxidant) and dairy.
- elric 6y agoThere is (virtually?) no vitamin D in cheese. Milk is fortified with vitamin D in some places, maybe that's what you're referring to?
- arcturus17 6y agoFrance has been hit extremely hard though.
- g8oz 6y agoAre they still not including deaths in retirement homes as part of the fatality count or did they backtrack on that?
- venj 6y agoThey are Included in the daily reports since beginning of April IIRC. The total number of fatalities also includes losses in retirement houses for March.
- triceratops 6y agoIndia has an extremely stringent lockdown.