4 ms·
(Med student here with only limited knowledge). This is correct. The active form of Vitamin D (Calcitriol) can be both helpful and harmful to bone health. I t
by thornjm 6y ago
(Med student here with only limited knowledge).
This is correct. The active form of Vitamin D (Calcitriol) can be both helpful and harmful to bone health.
I think the mechanism is not fully understood but in short doses it stimulates bone growth and is a treatment for osteoporosis. In chronic doses it actives cells caused osteoclasts that reabsorb bone.
- woofie11 6y agoDo you know the breakpoint? What's a short dose, and when does it become chronic?
- Harvesterify 6y agoCholecalciferol is used in over the counter supplements, not calcitriol (which is the active vitamin D form). There also is a negative feedback for the conversion, that explain why there are so few acute vitamin D poisoning.