Generally, if the patent is high quality, people settle because there isn't much to argue about. At most they do some preliminary hearings (claim construction)

Generally, if the patent is high quality, people settle because there isn't much to argue about. At most they do some preliminary hearings (claim construction) and then to a summary judgment hearing. The Alice case opened the door for awhile because practically any tech/computer related patent had a good change of being invalidated at summary judgment. I don't practice in bio so I am not familiar with CRISPR patents.