4 ms·
Estimates for the most recent common ancestor point to mid January for France [0]. Of course these numbers could be wrong. But I suspect the level of surveillan
by ImaCake 6y ago
Estimates for the most recent common ancestor point to mid January for France [0]. Of course these numbers could be wrong. But I suspect the level of surveillance of genomes allows for bioinformaticians to keep a close eye on what the virus is doing in a big picture evolution sense. They do note that while most samples are of `A2` strain virus (only meaningful at genotype level, not at phenotype) there were some samples from different genotype branches. Maybe their analysis finds the date for a later introduction of the virus which is different from the potential cryptic transmission occuring in late Dec?
0. http://virological.org/t/early-phylodynamics-analysis-of-the-covid-19-epidemics-in-france-using-194-genomes-april-10-2020/467 http://virological.org/t/early-phylodynamics-analysis-of-the...
- makomk 6y agoNote that their "slow molecular clock" estimate gives a most recent common ancestor around the end of December. They reject this because it "finds a root which seems very early given the data". It's also, of course, possible that this particular cluster died out entirely, got genetically bottlenecked, or only ended up causing a small proportion of cases just through random chance.