4 ms·

If I read this right this isn't based on any data, just a hypothesis because there is some similarity between the viruses. That's... a very low level of evidenc

by hannob 7y ago

If I read this right this isn't based on any data, just a hypothesis because there is some similarity between the viruses. That's... a very low level of evidence. It's a vague hypothesis, and one that is probably hard to test. Other than that: Absolutely get an MMR vaccine if you don't have one. I wouldn't cound on it helping against Covid-19, but it helps against the Measles, which is a good enough reason to get it anyway.

_Microft 7y ago
It's not just speculation on that level. Here is the conclusion from the linked paper verbatim: We identified at a population level that both older populations and males are both more likely to die from COVID-19, and less likely to be seropositive for rubella-specific immunity, based on historical vaccination programmes of all three countries considered in this report. Finally, the hypothesis that this macro domain could be recognised by antibodies raised against rubella was supported by data that demonstrated that patients who have SARS-CoV2 infection had raised levels of rubella IgG to a level in keeping with secondary rubella infection. Taken together, we suggest that MMR will not prevent COVID-19 infection but could potentially reduce poor outcome. To conclude whether MMR vaccination can improve the outcomes from Covid-19 infection, a study using individual based data to compare MMR immunity status in the affected population is warranted. Source: https://www.medrxiv.org/content/10.1101/2020.04.10.20053207v1.full.pdf#page=7 https://www.medrxiv.org/content/10.1101/2020.04.10.20053207v...
WrtCdEvrydy 7y ago
Maybe the reason there's been such a low rate of death is that the MMR vaccine had some effect on the Coronavirus? I'm not a scientist, I write Javascript.
- mrfusion 7y ago
  Do less Italians get the mmr? That would be interesting to look at the hard hit places.
  - mseri 7y ago
    Yes, children do
    - dnautics 7y ago
      Importantly, what about children 50+ years ago? In Italy
      - ghaff 7y ago
        Presumably mostly not. The original rubella vaccine was developed in the late sixties and the current vaccine (that's part of MMR) didn't come out until 1979.
- iso1210 7y ago
  In the UK MMR has been a standard vaccination for children born from 1990 onwards -- those born in the 80s (so in their 30s) only got measles+rubella, and those in the 70's (so in their 40s) only got measles. No evidence of any difference in deadliness between age ranges in under 50s in UK excess deaths.

by hannob 7y ago

_Microft 7y ago

It's not just speculation on that level. Here is the conclusion from the linked paper verbatim: We identified at a population level that both older populations and males are both more likely to die from COVID-19, and less likely to be seropositive for rubella-specific immunity, based on historical vaccination programmes of all three countries considered in this report. Finally, the hypothesis that this macro domain could be recognised by antibodies raised against rubella was supported by data that demonstrated that patients who have SARS-CoV2 infection had raised levels of rubella IgG to a level in keeping with secondary rubella infection. Taken together, we suggest that MMR will not prevent COVID-19 infection but could potentially reduce poor outcome. To conclude whether MMR vaccination can improve the outcomes from Covid-19 infection, a study using individual based data to compare MMR immunity status in the affected population is warranted. Source: https://www.medrxiv.org/content/10.1101/2020.04.10.20053207v1.full.pdf#page=7 https://www.medrxiv.org/content/10.1101/2020.04.10.20053207v...

WrtCdEvrydy 7y ago

Maybe the reason there's been such a low rate of death is that the MMR vaccine had some effect on the Coronavirus? I'm not a scientist, I write Javascript.

mrfusion 7y ago
Do less Italians get the mmr? That would be interesting to look at the hard hit places.
- mseri 7y ago
  Yes, children do
  - dnautics 7y ago
    Importantly, what about children 50+ years ago? In Italy
    - ghaff 7y ago
      Presumably mostly not. The original rubella vaccine was developed in the late sixties and the current vaccine (that's part of MMR) didn't come out until 1979.
iso1210 7y ago
In the UK MMR has been a standard vaccination for children born from 1990 onwards -- those born in the 80s (so in their 30s) only got measles+rubella, and those in the 70's (so in their 40s) only got measles. No evidence of any difference in deadliness between age ranges in under 50s in UK excess deaths.