3 ms·

By this definition you might argue that it's a vitamin north of some geographic line and a hormone south of that line .... Also, nicotinamide (one form of Vita

By this definition you might argue that it's a vitamin north of some geographic line and a hormone south of that line .... Also, nicotinamide (one form of Vitamin B3) is a metabolite of niacin (nicotinic acid, another form of Vitamin B3). Humans can produce the former from the latter, but require at least one of them from the diet. Does that make niacin a vitamin, but nicotinamide a hormone? They are not equivalent, but as far as "being essential", they are substitutes. (No idea myself, just rumbling thoughts)

ashtonkem 7y ago
I believe the capability of humans to synthesize sufficient amounts of D3 under many circumstances makes it a hormone, not whether or not I’m synthesizing it right now. It doesn’t suddenly go from being a hormone to a vitamin once I took up an office job, I just stopped doing the activities required to self-synthesize it. I think things get very tricky to define when you need at least one compound that can complete some biological process, but there are several different potential compounds that could do the job, some of which have to come from diet and others can by synthesized by the human body.
- Melting_Harps 7y ago
  > I believe the capability of humans to synthesize sufficient amounts of D3 under many circumstances makes it a hormone Its molecular structure precursor is cholesterol, a steroid hormone which by convention is a molecule with 3 hexanes attached to pentane and an R group, it under goes a series of cleaves in the presence of UV light to yield D3. D3 and its known analogue's behavioiur and bioactivety also behaves like a steroid/hormone in that it can passively diffuse across a membrane. and helps down-regulate other metabolic reactions. Its effects on reducing inflammation in IG patients is well documented and worth checking out. Here is a good review on Corticosteroids, specifically on there effects on inflammation treatment. https://www.medicinenet.com/corticosteroids_vs_nsaids/article.htm#what_are_corticosteroids_and_nsaids https://www.medicinenet.com/corticosteroids_vs_nsaids/articl...

ashtonkem 7y ago

I believe the capability of humans to synthesize sufficient amounts of D3 under many circumstances makes it a hormone, not whether or not I’m synthesizing it right now. It doesn’t suddenly go from being a hormone to a vitamin once I took up an office job, I just stopped doing the activities required to self-synthesize it. I think things get very tricky to define when you need at least one compound that can complete some biological process, but there are several different potential compounds that could do the job, some of which have to come from diet and others can by synthesized by the human body.

Melting_Harps 7y ago
> I believe the capability of humans to synthesize sufficient amounts of D3 under many circumstances makes it a hormone Its molecular structure precursor is cholesterol, a steroid hormone which by convention is a molecule with 3 hexanes attached to pentane and an R group, it under goes a series of cleaves in the presence of UV light to yield D3. D3 and its known analogue's behavioiur and bioactivety also behaves like a steroid/hormone in that it can passively diffuse across a membrane. and helps down-regulate other metabolic reactions. Its effects on reducing inflammation in IG patients is well documented and worth checking out. Here is a good review on Corticosteroids, specifically on there effects on inflammation treatment. https://www.medicinenet.com/corticosteroids_vs_nsaids/article.htm#what_are_corticosteroids_and_nsaids https://www.medicinenet.com/corticosteroids_vs_nsaids/articl...