3 ms·
I found this news exciting/significant because this is the first time we've seen positive news about remdesivir in the context of a placebo controlled, randomiz
by vikramkr 7y ago
I found this news exciting/significant because this is the first time we've seen positive news about remdesivir in the context of a placebo controlled, randomized, double blinded trial. Unlike prior trials that either didnt have a control arm, or trials like the Lancet trial that was also released today that were underpowered, this trial shows a statistically significant effect by remdesivir. For context, the Lancet trial showed a numerical effect, but couldn't recruit enough patients and was ultimately underpowered, so it wasnt able to show statistical significance.
It's exciting that there's finally at least one drug with at least one fully powered thousand plus patient placebo controlled trial with a statistically significant impact. It shows the disease is drug gable and treatable, and is not invulnerable, and is an exciting win for science.
Something else I'm excited about is the potential to use Remdesivir as a preventative. Because it works by inhibiting viral replication, it could be used as a preventative for high risk individuals until a vaccine is developed or the disease is eradicated.