3 ms·
From a nurse in Wuhan who is a family friend: It seemed clear to her and her coworkers that Remdesivir was working when given early, but had little or no effect
by lowdest 6y ago
From a nurse in Wuhan who is a family friend: It seemed clear to her and her coworkers that Remdesivir was working when given early, but had little or no effect after the disease had progressed.
My take: sounds like great news for a product, since everyone would want this on hand to catch infections early. Unfortunately it is an IV treatment and very difficult to manufacture, and is therefore unlikely to be able to fill that role. I bought a few shares anyway.
- yonaguska 6y agoIsn't that effectively the same result with hydroxychloroquine + z-paks?
- deleted 6y ago[deleted]
- DylanBohlender 6y agoSounds like it (I've also heard of zinc being added in with HCQ and the z-pak as part of that treatment protocol, sometimes called the "Raoult protocol" and referred to hereafter as such for brevity). Both the Raoult protocol and remdesivir appear to help if used earlier in the disease progression; neither seem to do anything if the disease has progressed past a certain point. If early use is the key to efficacy (and if both demonstrate the same degree of efficacy, as it seems currently), the Raoult protocol is the only one that makes sense to scale up. The ingredients for the Raoult protocol are much more easily mass-produced and administered, whereas remdesivir is proprietary, very expensive, and IV-only (as other posters have noted).
- yumraj 6y agoSounds similar to how Tamiflu works for seasonal Flu. Does remdesivir work on coronavirus in a similar fashion?
- usaar333 6y agoCompletely different. Tamiflu blocks influenza viruses from being released from its host cell (https://en.wikipedia.org/wiki/Neuraminidase_inhibitor https://en.wikipedia.org/wiki/Neuraminidase_inhibitor) Remdesivir interferes with viral replication itself (https://en.wikipedia.org/wiki/Remdesivir https://en.wikipedia.org/wiki/Remdesivir)
- seemslegit 6y agoDid she consider it might be due to a selection effect of people who arrive to the hospital in mild rather than severe stages of the disease ?