Certainly it would be necessary to ensure people are of sound mind and understand the risk they're taking. That said, if we're talking about young, healthy peo

Certainly it would be necessary to ensure people are of sound mind and understand the risk they're taking. That said, if we're talking about young, healthy people volunteering, and given they will be monitored throughout the trial, I would guess their risk of death would be on the order of 1/1000, if not better. (Based on recent estimates of overall CFR on the order of 0.5% out of NYC and such.) That's not a risk I personally would want to take, but it's on the order of the risk people take when donating a kidney. (And of course for most people the process will be much less arduous than a kidney donation.) We consider that acceptable to save a single life, whereas a faster vaccine would save many. So my prior would be that most people volunteering for something like this are simply altruistic, similar to a kidney donor, rather than mentally ill.