4 ms·
Without looking into the pharmacology of modafinil, this is a baseless comment. Seriously, look at the pharmacology of modafinil[1] and compare it to methylphen
by TheAdamAndChe 6y ago
Without looking into the pharmacology of modafinil, this is a baseless comment. Seriously, look at the pharmacology of modafinil[1] and compare it to methylphenidate[2]. Modafinil may have some dopamine reuptake inhibition, but its affect on histamine receptors counters a lot of the hedonistic response that comes with methylphenidate.
Speaking as someone with a modafinil prescription and that has taken Vyvanse, the experience is extremely different. I don't feel an urge to take more modafinil, and I don't feel extreme fatigue when taking a break from it. I'm taking a break from it now in fact.
[1] https://en.wikipedia.org/wiki/Modafinil https://en.wikipedia.org/wiki/Modafinil
[2] https://en.wikipedia.org/wiki/Methylphenidate https://en.wikipedia.org/wiki/Methylphenidate