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Not exactly true. Moderna, and several others who are leading the vaccine race right now are out front because they had viable SARS and MERS vaccines but no whe
by CyanLite4 6y ago
Not exactly true. Moderna, and several others who are leading the vaccine race right now are out front because they had viable SARS and MERS vaccines but no where to test it other than in animal models.
Coronaviruses are easy to vaccinate against. They mutate very slowly. There’s just not a viable business model for them when the symptoms are so mild and treatments are available cheaply over-the-counter.
- gridlockd 6y ago> Coronaviruses are easy to vaccinate against. From what I've read, creating a sufficiently safe vaccine has been quite a challenge.
- aledalgrande 6y ago> Coronaviruses are easy to vaccinate against. They mutate very slowly. Wait can you expand on that? I thought RNA viruses mutate very quickly?
- totony 6y agoFrom what I understand, covid is a relatively small rna strand vs e.g. the flu which makes significant mutation way more rare
- rotexo 6y agoSARS-CoV-2 genome size is ~30 kb [1], influenza A genome size is ~14 kb [2]. A protein encoded in the SARS-CoV-2 genome is predicted to have exonuclease proofreading activity, which would result in a lower mutation rate [3]. [1] https://mra.asm.org/content/9/11/e00169-20 https://mra.asm.org/content/9/11/e00169-20 [2] https://en.m.wikipedia.org/wiki/Influenza_A_virus#Structure_and_genetics https://en.m.wikipedia.org/wiki/Influenza_A_virus#Structure_... [3] https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02344-6 https://translational-medicine.biomedcentral.com/articles/10...