3 ms·
> No evidence supports the hypothesis that single codon or single nucleotide deletions correlate with attenuation of strains https://www.mdpi.com/1999-4915/11/
by T-A 7y ago
> No evidence supports the hypothesis that single codon or single nucleotide deletions correlate with attenuation of strains
https://www.mdpi.com/1999-4915/11/11/1016 https://www.mdpi.com/1999-4915/11/11/1016
- lvs 7y agoThe citation does not refute or pertain to my statement. Yes, very specific mutations/indels can attenuate strains -- welcome to biology -- but the broad claim that the general observation of mutations/indels is somehow indicative of attenuated strains circulating in the wild is entirely unsupported and facially ridiculous.
- danieltillett 7y agoI am not claiming any of this. I am saying that the right type of mutations exist in the SARS-CoV-2 genomes that attenuated strains COULD exist. If they do I am arguing we should look for them rather than sitting in our armchairs coming up with possible reasons they don’t and so not even bothering.