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Hi Daniel, When you first put up the idea, it seemed like your emphasis was on using the attenuated strain directly as a vaccine (and benefiting from its abilit
by musiciangames 6y ago
Hi Daniel,
When you first put up the idea, it seemed like your emphasis was on using the attenuated strain directly as a vaccine (and benefiting from its ability to propagate itself). This post suggests more to help test a conventional vaccine.
Could you comment on reasons for the change of approach?
- danieltillett 6y agoYes that is right. While the idea of using such a strain as a vaccine directly was the focus of my first post, this was controversial. Even if you think it is too risky to use a natural attenuated strain as a vaccine, such as strain would be very useful as a tool to accelerate other vaccines. As I said in my first post how to use any such strain is not up to me, but if it can be used to get us to a vaccine sooner it is worth looking into. If we are going consider doing a challenge trial we should at first make the effort to see if we can find a safer strain to use.