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> Vaccines that fail safety do not get manufactured. Vaccines with documented adverse affects do not get manufactured All good in theory, except you only find

by 1996 6y ago

> Vaccines that fail safety do not get manufactured. Vaccines with documented adverse affects do not get manufactured All good in theory, except you only find rare side effects like autoimmune disorders during postmarket studies. So again, "no plan survives contact with the enemy" This is the reason why old drugs are generally safer than new drugs: they have been "tested" on millions of patients.

ksk 6y ago
Well if anything serious is found post-sale then like any medication, a recall should be issued. But like you said, all good in theory :) If any vaccine manufacturer engages in fraud and massages the data, then that is a human greed issue, not really unique to our industry. I do make a distinction between pharmaceutical and biologics though. But on the whole I would say that due to the strong regulatory framework in place, and the active role that the FDA plays, we have less of that compared to other industries like finance/markets for e.g.
- Madmallard 6y ago
  There are so many awful drugs still in use that have taken decades for people to rile up enough of a backlash for the FDA to do something about it. And even then they're bought out to do things like "blackbox warnings" instead of take drugs off the market. These warnings basically are 'we should take the drug off the market because it causes serious problems' but it never happens. Take fluoroquinolones for example. In use since the 70s. Studies since the 90s knew about serious toxic adverse effects. Took until just this last decade for their use to become limited, with an unknown number of people whose lives have been likely ruined or terminated by the drugs.
Madmallard 6y ago
You literally cannot know what is causing the auto-immune responses through current research methods. There are way too many factors and variables to weed through yet it's becoming more and more prevalent.

by 1996 6y ago

ksk 6y ago

Well if anything serious is found post-sale then like any medication, a recall should be issued. But like you said, all good in theory :) If any vaccine manufacturer engages in fraud and massages the data, then that is a human greed issue, not really unique to our industry. I do make a distinction between pharmaceutical and biologics though. But on the whole I would say that due to the strong regulatory framework in place, and the active role that the FDA plays, we have less of that compared to other industries like finance/markets for e.g.

Madmallard 6y ago
There are so many awful drugs still in use that have taken decades for people to rile up enough of a backlash for the FDA to do something about it. And even then they're bought out to do things like "blackbox warnings" instead of take drugs off the market. These warnings basically are 'we should take the drug off the market because it causes serious problems' but it never happens. Take fluoroquinolones for example. In use since the 70s. Studies since the 90s knew about serious toxic adverse effects. Took until just this last decade for their use to become limited, with an unknown number of people whose lives have been likely ruined or terminated by the drugs.

Madmallard 6y ago

You literally cannot know what is causing the auto-immune responses through current research methods. There are way too many factors and variables to weed through yet it's becoming more and more prevalent.