Sorry, typo. I meant SPR (surface plasmon resonance). I’ve worked at a number of NGS platform companies developing new sequencing approaches. The problem is th

Sorry, typo. I meant SPR (surface plasmon resonance). I’ve worked at a number of NGS platform companies developing new sequencing approaches. The problem is that sequencing is still expensive at the per-run level. It’s possible to be cost competitive with qPCR if you multiplex samples. But this isn’t ideal. It would be interesting to create a small/cheap sequencer which could be applied to point-of-care/at-home testing. However, most of the money has gone after attacking the market leader (Illumina) on a cost-per-base, rather than cost-per-run. A 1USD per-run sequencer would be interesting. But I’ve not seen anything that will hit that target in development. If anyone reading this is developing such a system, let me know, I’d love to get involved. The idea of a programmable qPCR system is to add some of the versatility of sequencing to qPCR.