4 ms·

I’m having difficulty understanding why SPR would be more scalable than LFAs for this type of frequent screening? And what does the ROC look like for this start

by IdoRA 6y ago

I’m having difficulty understanding why SPR would be more scalable than LFAs for this type of frequent screening? And what does the ROC look like for this startup’s SPR assay? Frankly, I don’t understand how this test is supposed to work, and I’ve used a Biacore! It might be helpful to have a technical explanation available, for domain experts to evaluate.

s0rce 6y ago
There didn't seem to be any details at all. Is there some sort of functionalized surface that specifically binds the virus, if so what molecule/chemistry, how? edit: this is all I found about the company: https://www.sbir.gov/sbirsearch/detail/1564207 https://www.sbir.gov/sbirsearch/detail/1564207 https://innovation.medicine.umich.edu/portfolio_post/sepsis-risk-measurement-device/ https://innovation.medicine.umich.edu/portfolio_post/sepsis-...
- deleted 6y ago
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- predxionbio 6y ago
  Good sleuthing! As you suspect we functionalize the our sensor surface to specifically bind the virus. We've partnered with a therapeutics company developing highly specific monoclonal mAbs against SARS-CoV-2 which we leverage in our diagnostic platform.