Yes, many: Godot has a 2D renderer and physics option, Defold is 2D by default, Game Maker Studio, Cocos2d, Corona, Construct, Phaser.io, Buildbox, Gamesalad,

Yes, many: Godot has a 2D renderer and physics option, Defold is 2D by default, Game Maker Studio, Cocos2d, Corona, Construct, Phaser.io, Buildbox, Gamesalad, Stencyl, Clickteam Fusion Unity is very capable of 2d games too and provides a lot of game structure and so do many other engines (I want to mention Heaps.io because it’s awesome).