Not really in this case though. Ethically there's not much of a concern with that study since we don't know what works so we're not doing any harm by prescribin

Not really in this case though. Ethically there's not much of a concern with that study since we don't know what works so we're not doing any harm by prescribing known bad methods. The ethical harm would come from a poor study design that won't tell us anything useful. Getting good data from a study like this is really difficult, and we can't really accomplish anything by discarding good data for the sake of efficiency