I am using a 1200p, a 1800p and a 2160p monitor side-by-side on MacOS and it works fine. The 2160p monitor is rotated to portrait mode for reading/writing text

I am using a 1200p, a 1800p and a 2160p monitor side-by-side on MacOS and it works fine. The 2160p monitor is rotated to portrait mode for reading/writing text documents. I can hotplug a monitor and it will automatically switch to the right layout, remembering the correct location for all open windows. I am using a 1080p and a 2160p on ArchLinux/Wayland/Gnome3. It's not perfect, but it's not unusable either (compared to X11, which was completely broken).