Be careful thinking about potential cost of bringing a synthesis to market based on Sigma Aldrich catalog prices. SA is a supply house for research chemicals, p

Be careful thinking about potential cost of bringing a synthesis to market based on Sigma Aldrich catalog prices. SA is a supply house for research chemicals, prioritizing quantity of compounds offered and consistent, specified quality over price. The range of products they offer is insane, even considering the reactivity and instability of some of them. If your commercialize a compound, you source these starting materials (eg. Bromoindole) directly through manufacturers. You will be able to buy in bulk at 10-1000x lower prices, sometimes. Of course you need to do judicious quality controls yourself, but you likely have the scaling benefits to do.