So the culture issue you raise definitely presents some unrecoverable aspect, but as for the biology, there's certainly a path. We have animals now that are cl

So the culture issue you raise definitely presents some unrecoverable aspect, but as for the biology, there's certainly a path. We have animals now that are closely enough related to extinct animals that we could conceivably bring them back through incremental genetic modifications. For example, if we wanted to bring back Direwolves, we could edit the DNA of a gray wolf maximally such that it can still be fertile and be born by a non-edited gray wolf. This would give you a wolf closer to a Direwolf and then you could repeat this process using each previous generation as the carrying mother for the genetically modified embryo.