5 ms·
Gilead data suggests coronavirus patients are responding to treatment
- refurb 6y agoAt his wife’s urging, Michalak went to the University of Chicago Medicine hospital on Friday, April 3....and recovered enough to be discharged from the hospital on Tuesday, April 7. That's pretty impressive to be a severe case of COVID and be discharged 4 days later.
- wbhart 6y agoTrue, but that could be a single cherry-picked example just for the article. It does sound like the typical case might not be too far off that though, which is potentially very good news.
- refurb 6y agoOf course. It’s one patient with no control. Still, that seems like a quick recovery drug or not.
- mcfunk 6y agoSounds better than typical but not "cherry-picked" either, for the people treated-- of 125 patients: >She added: “Most of our patients are severe and most of them are leaving at six days, so that tells us duration of therapy doesn’t have to be 10 days. We have very few that went out to 10 days, maybe three,” she said. So again, not conclusive, but sounds like it is surprising medical professionals used to seeing 10 day stays for COVID patients.
- jdkee 6y agoIt happens regularly. COVID-19 patients need O2 for a few days and then are titrated back down to room air and discharged.
- smallgovt 6y agoStock futures are up 3% on this news so there appears to be something to this.
- deleted 6y ago[deleted]
- Leary 6y agoGilead itself is up 16%, which would be a 52 week high.
- empath75 6y agoIt’s an extremely difficult drug to manufacture and they may not be able to ramp it up in the next few months. Which is to say it’s good news for the second wave that’s coming but we can’t open up yet.
- jlokier 6y agoIf it works well, and the only problem is manufacturing, there's an entire planet full of emergency-funded researchers and manufacturing engineers who would be very interested in solving the fast manufacturing problem. It sounds a lot easier than the problem of finding good drugs in the first place, to be honest.
- jandrese 6y ago3% in the futures market is just noise.
- smallgovt 6y agoIf you were doubting that the +3% market movement was primarily driven by this news, take a look at the markets at 12:40PM today when negative news of clinical trials for the drug were released. Again, direct minute by minute correlation btw SPY dropping and GILD news.
- loopz 6y agoThe rally from bottom isn't though. Infinite currency makes for risk on.
- nayuki 6y agoThe fact that they don't have a control group is not a good sign: > Mullane, while encouraged by the University of Chicago data, made clear her own hesitancy about drawing too many conclusions. “It’s always hard,” she said, because the severe trial doesn’t include a placebo group for comparison. Here is some historical perspective about using placebos while people are getting infected and dying: * https://rootsofprogress.org/polio-and-the-controversy-over-randomized-clinical-trials https://rootsofprogress.org/polio-and-the-controversy-over-r... * https://rootsofprogress.org/more-on-polio-and-randomized-clinical-trials https://rootsofprogress.org/more-on-polio-and-randomized-cli...
- xiphias2 6y agoWhy was it even allowed? Isn't there some requirement for a trial to be called Phase 3? A Google search resulted in this: The third step in testing an experimental drug (or other treatment) in humans. Phase 3 trials are conducted to confirm and expand on safety and effectiveness results from Phase 1 and 2 trials, to compare the drug to standard therapies for the disease or condition being studied, and to evaluate the overall risks and benefits of the drug. https://clinicaltrials.gov/ct2/show/NCT04292899 https://clinicaltrials.gov/ct2/show/NCT04292899 ,,Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)'' The title doesn't contain Efficacy :( A better clinical trial (but with fewer participants) will be run in Norwegia, but we're supposed to get results only in August. I don't understand why we're losing so much time by not running studies all the time. https://clinicaltrials.gov/ct2/show/NCT04321616?term=Remdesivir&draw=2&rank=8 https://clinicaltrials.gov/ct2/show/NCT04321616?term=Remdesi...
- glennericksen 6y agoNorwegia aka Norway :) "Because Indonesians come from Indonesia, and Russians come from Russia, Norwegians come from Norwegia." - Urban Dictionary
- perl4ever 6y agoRecently I learned that the demonym for San Marino is "Sammarinese".
- vardump 6y agoCompany says their product test performance is great. News at 11. Cautiously optimistic, let's hope and see. And not be too disappointed if this turns out to be nothing.
- Lidador 6y agoI've heard Gilead was a fake news hoax planted by Adam Feuerstein...
- robodale 6y agoIf this goes sour...stock market go down arrow. (It's been propped up on hopes treatments like this will work).