Perhaps, though in this case I'd put that burden as relatively weak. That is, we know that in principle it could have been made, even if we don't (publicly) kn

Perhaps, though in this case I'd put that burden as relatively weak. That is, we know that in principle it could have been made, even if we don't (publicly) know how that would have been done in 2019. An additional important point is that there's a middle scenario where a natural virus being studies could have been accidentally mutated and accidentally released. This might be all but impossible to distinguish between origin in the wild. I'd guess intentional manufacture as very unlikely, but sloppy lab practices as not likely but much more likely than that.