There are two potential benefits of hcq people are hoping to prove: first as an antiviral, secondly as an immuno modulator for the IL-6 pathway. As a nonspecifi

There are two potential benefits of hcq people are hoping to prove: first as an antiviral, secondly as an immuno modulator for the IL-6 pathway. As a nonspecific antiviral any benefit tends to be for the early stage of the disease, possibly as a prophylaxis or preventive. So to me this trial mostly shows that there is no discernible benefit for hcq as an immuno-modulator. That is disappointing but not too surprising. I hear people with autoimmune problems say that it takes a month or two for the drug's effect to kick in. That is about 12g of cumulative dose, too big to reach in a short time without acute toxicity. I wonder here if also people of the high risk group could benefit from prophylactic use. Is there any truth to the claim that lupus patients on hcq don't suffer from covid? This claim should be easy to check now that we have so many cases of covid around the world.