3 ms·

Besides that study just being in vitro (which is promising, but far from conclusive), the concentrations they needed to have an effect were really high: https:/

Besides that study just being in vitro (which is promising, but far from conclusive), the concentrations they needed to have an effect were really high: https://sciencebasedmedicine.org/are-hydroxychloroquine-and-azithromycin-an-effective-treatment-for-covid-19/ https://sciencebasedmedicine.org/are-hydroxychloroquine-and-... > I also note that the half-maximal effective concentration (EC50) for blocking viral replication in vitro was 1.13 μM and the half-cytotoxic concentration (CC50) was greater than 100 μM. These are high concentrations for a drug, especially the CC50.

rurban 7y ago
You need these high concentrations if you apply them too late. HCQ needs a few weeks to settle in the cells. What I want to see are studies applying HCQ before the infection (that's what the Chinese measured, Lupus patients being immune), are at least when they were tested positive and sent home. Not when the shit already hit the fan, and the mucus is in the lungs causing bacterial infections all over. Because then it's too late already.