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Leaked paper submitted to NEJM suggests hydroxychloroquine ineffective
- tannerbrockwell 7y agoHopefully we get some update on the WHO test that is announced in this document: "20,000 healthcare workers [will receive] chloroquine [and] will be tested daily as currently used in the treatment of rheumatoid arthritis for three months or until they are diagnosed with COVID-19." [1] [1]: https://www.who.int/blueprint/priority-diseases/key-action/RD-Blueprint-expert-group-on-CQ-call-Mar-13-2020.pdf https://www.who.int/blueprint/priority-diseases/key-action/R...
- rurcliped 7y agoI don't work in this field, but the authors seem to be suggesting that hydroxychloroquine makes some things significantly worse. Patients who took hydroxychloroquine were much more likely to "need" supplementary oxygen. However, the two groups of patients were in two different hospitals. The paper doesn't discuss whether each hospital used exactly the same definition of "need" and had staff policies/practices that assessed this need with exactly the same amount of diligence.
- gus_massa 7y agoI agree. From the article: > This created a unique situation in which natural randomization occurred depending on which hospital they were admitted to. As someone that goes to every thread about the French study to highlight that it has no real control group, I'm morary obliged to point here that this study has no real control group (in spite it has somewhat the oposite conclussion).