I also have a Logitech MX Master 2S, on Arch Linux, and it has been working flawlessly since the beginning. But the device was introduced in 2017, and you ment

I also have a Logitech MX Master 2S, on Arch Linux, and it has been working flawlessly since the beginning. But the device was introduced in 2017, and you mention Ubuntu 16. Newer devices require newer drivers.