Absolutely not. Not only do Guzey's nitpicks not refute the main point, they fail to refute even the subpoints and subsubpoints. The example cited here, where

Absolutely not. Not only do Guzey's nitpicks not refute the main point, they fail to refute even the subpoints and subsubpoints. The example cited here, where people on 5 hours of sleep actually have slightly less chance of injury than 6, is by far the most egregious one, but even it doesn't change the conclusion of the sentence where it appears. At most, it would require a footnote: "also, something weird is going on in the tiny 5 hour group".