3 ms·
I've read that ACE and ARB inhibitors promote the generation of nitric oxide.
by pkaye 7y ago
I've read that ACE and ARB inhibitors promote the generation of nitric oxide.
- youareostriches 7y agothe hypothesis about ACE inhibitors and ARBs promoting covid-19 severity has never been proven in any human study and in fact ARBs have been shown to reduce mortality in one of the few covid studies which have been done: Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients https://www.medrxiv.org/content/10.1101/2020.03.20.20039586v1 https://www.medrxiv.org/content/10.1101/2020.03.20.20039586v...
- pkaye 7y agoI'm not saying that ACE/ARBs promote covid19 severity but rather they promote nitric oxide production.
- youareostriches 7y agoYes, they do that. It would be consistent with the results seen: Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust https://www.medrxiv.org/content/10.1101/2020.04.07.20056788v1 https://www.medrxiv.org/content/10.1101/2020.04.07.20056788v...