4 ms·
Actual article [it's open access]: https://www.nature.com/articles/s41541-020-0172-y https://www.nature.com/articles/s41541-020-0172-y Pleasantly surprised to
by mattkrause 7y ago
Actual article [it's open access]: https://www.nature.com/articles/s41541-020-0172-y https://www.nature.com/articles/s41541-020-0172-y
Pleasantly surprised to see that it's not yet another amyloid-targeting approach that works great in mice but will inevitably bomb in humans (just like the last dozen Aß trials).
- ncmncm 7y agoIt seems amply demonstrated that the mouse model of the disease is different enough from the actual disease that any given mouse result tells us nothing about the disease, or what may cause or cure it. But there are very many researchers who know a great deal about the mouse model. It is not clear whether. any know about the human disease; or, if any do, whether the mouse modelers pay them any attention.