3 ms·
I could go on and on about zinc. ACE2 is a zinc metalloproteinase, contains two zinc ions and uses zinc as a cofactor. Hey, you know, maybe that is why it is go
by podgaj 7y ago
I could go on and on about zinc. ACE2 is a zinc metalloproteinase, contains two zinc ions and uses zinc as a cofactor. Hey, you know, maybe that is why it is good becasue SAARS-CoV-2 happens to drag ACE2 INTO the cell so maybe the zinc it drags in helps inhibit the virus? Just a thought.
But zinc is also a cofactor for ADAM17 which is responsible for shedding ACE2 from the cell. It is a possible route to lower cellular replication of the virus if the ACE2 cannot enter the cell.