3 ms·

How do we know that a less deadly strain actually provides some immunity to a more deadly strain? That seems like an assumption here.

Amygaz 7y ago
His assumption is based on live-attenuated vaccines. The measles vaccine being one of those. All the early vaccines where like that. The process only requires heat inactivation. So you end up with a dead or almost dead virus, which can't replicate anymore. Your immune system recognizes it as a foreign agent, makes antibodies to tag it for removal. Today we prefer to immunize with a part of the virus structure, which end up doing the same thing.
- annoyingnoob 7y ago
  Still seems like an assumption until its tested/proven. I'd prefer a more evidence based approach, evidence from this virus.
  - danieltillett 7y ago
    You can only get evidence if you go out and collect the evidence. I am proposing a way we can actually collect this evidence. Saying something won’t work because there is no evidence when you haven’t look for any evidence is not very logical.
    - annoyingnoob 7y ago
      Just questioning assumptions, in a healthy skepticism kind of way. I have no expertise here. There is a lot of speculation and general fud surrounding covid-19, seems right to question potential 'solutions' when we are light on facts. To be clear, I never said it wouldn't work, I'm saying that it looks like you assume it will work.
      - danieltillett 7y ago
        I most certainly have not assumed it will work, in fact I say there is a pretty good chance it won’t. What I do think it could work and that the cost in minor compared to the payoff if it does work.
        annoyingnoob 7y ago
        In which case, we need to think about Medical Ethics. Do we start experimenting with you and your loved ones?
        danieltillett 7y ago
        Nobody is being experimented on or proposed to be experimented on. The proposal is to go and look for an attenuated strain and then decide what to do with it if we find one.
        annoyingnoob 7y ago
        https://www.npr.org/sections/coronavirus-live-updates/2020/04/25/844939777/no-evidence-that-recovered-covid-19-patients-are-immune-who-says https://www.npr.org/sections/coronavirus-live-updates/2020/0...
spuz 7y ago
You'd have to sample many thousands of people who either have no symptoms or got sick. If the strain only exists in people with no symptoms then there's a good chance it's not deadly or at least less deadly than the other strains. Of course you might find the best strain you can find exists in 100% of asymptomatics and 20% of the dead. That would indicate your strain has some non-zero death rate.

Amygaz 7y ago

His assumption is based on live-attenuated vaccines. The measles vaccine being one of those. All the early vaccines where like that. The process only requires heat inactivation. So you end up with a dead or almost dead virus, which can't replicate anymore. Your immune system recognizes it as a foreign agent, makes antibodies to tag it for removal. Today we prefer to immunize with a part of the virus structure, which end up doing the same thing.

annoyingnoob 7y ago
Still seems like an assumption until its tested/proven. I'd prefer a more evidence based approach, evidence from this virus.
- danieltillett 7y ago
  You can only get evidence if you go out and collect the evidence. I am proposing a way we can actually collect this evidence. Saying something won’t work because there is no evidence when you haven’t look for any evidence is not very logical.
  - annoyingnoob 7y ago
    Just questioning assumptions, in a healthy skepticism kind of way. I have no expertise here. There is a lot of speculation and general fud surrounding covid-19, seems right to question potential 'solutions' when we are light on facts. To be clear, I never said it wouldn't work, I'm saying that it looks like you assume it will work.
    - danieltillett 7y ago
      I most certainly have not assumed it will work, in fact I say there is a pretty good chance it won’t. What I do think it could work and that the cost in minor compared to the payoff if it does work.
      - annoyingnoob 7y ago
        In which case, we need to think about Medical Ethics. Do we start experimenting with you and your loved ones?
        danieltillett 7y ago
        Nobody is being experimented on or proposed to be experimented on. The proposal is to go and look for an attenuated strain and then decide what to do with it if we find one.
        annoyingnoob 7y ago
        https://www.npr.org/sections/coronavirus-live-updates/2020/04/25/844939777/no-evidence-that-recovered-covid-19-patients-are-immune-who-says https://www.npr.org/sections/coronavirus-live-updates/2020/0...

spuz 7y ago

You'd have to sample many thousands of people who either have no symptoms or got sick. If the strain only exists in people with no symptoms then there's a good chance it's not deadly or at least less deadly than the other strains. Of course you might find the best strain you can find exists in 100% of asymptomatics and 20% of the dead. That would indicate your strain has some non-zero death rate.