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You really want to find every single person who has been infected with the mutant strain and find out how sick they got. If you find a mutant that infected 10,0
by danieltillett 7y ago
You really want to find every single person who has been infected with the mutant strain and find out how sick they got. If you find a mutant that infected 10,000 people and didn’t cause any serious illness then you have a pretty good idea it safe.
- NyxWulf 7y agoI think the point is that you have to sequence people in the hospital as well, otherwise you won't know if that particular strain is safe or not. If it is a rare strain, how will you know if it's safe? Seems like it would have to be a rare strain with thousands of cases and hospitalizations in that population are extremely rare. Sampling bias and other confounding factors would be a real problem in this search, at least from a statistical point of view, imo. I also think finding everyone who has been infected with a strain isn't feasible, at best you are sampling from the population.
- danieltillett 7y agoYou actually want to screen all people in the local area for the strain that may have it. If all the people have had a mild case and none of them are in hospital then you have something special.