20ms rtt through e.g. opus on a loopback network interface is already decidedly non-trivial to archive with "normal" hardware. When you do have low-latency devi

20ms rtt through e.g. opus on a loopback network interface is already decidedly non-trivial to archive with "normal" hardware. When you do have low-latency devices, it becomes easy, but not everyone has those. USB should not really be an issue here, however.