Probably not directly, but the mechanisms we evolve are generalized to some degree, i.e they often end up being useful for things our ancestors never encountere

Probably not directly, but the mechanisms we evolve are generalized to some degree, i.e they often end up being useful for things our ancestors never encountered. Perhaps the method by which we smell give us a similar sense for some similarly hazardous molecules. According to the wiki O3 smells much like Chlorine, they are both highly oxidizing which is why they can be hazardous.