Re:placebo, these were people with treatment-resistant depression. They've had depression for many years, have undergone many rounds of medication and talk ther

Re:placebo, these were people with treatment-resistant depression. They've had depression for many years, have undergone many rounds of medication and talk therapy (I've been through 7 drugs including ketamine, and 3 therapists). This is not a group that is prone to placebo improvements, they're cynical and hopeless, though of course a double-blind study is still needed.