That's one of the goals of the Clojure team. While the main 'branch' targets the JVM, there is also a branch targeting .NET. And there is an initiative, Cloju

That's one of the goals of the Clojure team. While the main 'branch' targets the JVM, there is also a branch targeting .NET. And there is an initiative, Clojure-in-Clojure, to de-couple the main branch from the JVM as much as possible, to facilitate re-targeting.