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Right, with this and chloroquine, assuming it works to prevent the virus from binding to ACE2, you'd want it to be in the early stages, before massive damage to
by droithomme 7y ago
Right, with this and chloroquine, assuming it works to prevent the virus from binding to ACE2, you'd want it to be in the early stages, before massive damage to the lungs, liver, intestines and brains are done (all of these are targeted by this virus). All other countries that are testing these are giving the drugs to patients in both the early and late stage of the infection. In the US alone, trials are only being done in the very late stage, after permanent damage has been done, and it's less likely to be of much use.
- HarryHirsch 7y agoThere is a large-scale clinical trial with 3000 participants (https://clinicaltrials.gov/ct2/show/NCT04308668 https://clinicaltrials.gov/ct2/show/NCT04308668) to see if chloroquine prevents progression to severe disease when given shortly after exposure, because when patients are symptomatic it was proved to be completely useless. There isn't a shortage of participants, and at that scale we'll know soon enough if Trump's wonder drug does something. Probably it won't.