4 ms·
>The safety and efficacy are not yet known so while we feel the greatest sense of urgency in our work with remdesivir, we must take the responsible, ethical app
by daenz 7y ago
>The safety and efficacy are not yet known so while we feel the greatest sense of urgency in our work with remdesivir, we must take the responsible, ethical approach of determining whether it is indeed a safe, effective treatment.
>we continue to provide remdesivir on an individual compassionate use basis for children and pregnant women.
Can someone explain this logic to me? The safety and efficacy is not known, so we're going to give it to the most vulnerable people first?
- ISL 7y agoIf someone is going to die anyway, a research drug that might save them sounds pretty awesome.
- deleted 7y ago[deleted]
- Waterluvian 7y agoBut children are of least concern. Or do they mean children who are going to die? How many instances of that are there? And pregnant women? That's hard to reconcile with common sense.
- dpbriggs 7y agoAre you unaware that judgement will be used? Compassionate uses are hail marys and are used appropriately.
- kayfox 7y agoSome more info on Compassionate Use: https://www.cancer.org/treatment/treatments-and-side-effects/clinical-trials/compassionate-drug-use.html https://www.cancer.org/treatment/treatments-and-side-effects...
- solotronics 7y agoIt works but they don't have enough for everyone.
- yellow_lead 7y agoThese are already patients who are in serious condition and this may be their last hope. AFAIK (at least pre-COVID rule changes), experimental treatments like these are only used at a patient's last resort, as stated by the FDA.
- nknealk 7y agoMayo Clinic has a really good writeup of the trade offs associated with compassionate use: https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/compassionate-use/faq-20058036 https://www.mayoclinic.org/healthy-lifestyle/consumer-health... Essentially, if a patient has no other options and might die, the FDA allows the use of unproven drugs.