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"liquid chromatography, is frequently used. On a small scale this is fine, but when kilograms of material are required the process becomes unwieldy." I did not
by joyj2nd 7y ago
"liquid chromatography, is frequently used. On a small scale this is fine, but when kilograms of material are required the process becomes unwieldy."
I did not understand this. liquid chromatography scales up quite well. There are other methods like Electorphoresis, salt precipitations etc., that don't.
- Metacelsus 7y ago>liquid chromatography scales up quite well Not compared to recrystallization or distillation. Try running a column on 10kg scale and get back to me. (I worked in an o-chem lab for 2 years in undergrad, and the biggest we could do was ~20 grams at once)