The roots of the plant Cryptolepis, also known as yellow-dye root, was found to be very effective against Lyme disease. So was the the Japanese Knotweed: https:

The roots of the plant Cryptolepis, also known as yellow-dye root, was found to be very effective against Lyme disease. So was the the Japanese Knotweed: https://blog.frontiersin.org/2020/02/21/ethnobotanical-medicine-is-effective-against-the-bacterium-causing-lyme-disease/ https://blog.frontiersin.org/2020/02/21/ethnobotanical-medic... Cryptolepis contains quinine and used by some tribes in West Africa to treat malaria.