4 ms·
The cell is an analog computer, but one who's computational state we are still working out describing (it consists of the concentrations of transcription factor
by mjfl 7y ago
The cell is an analog computer, but one who's computational state we are still working out describing (it consists of the concentrations of transcription factors as well as epigenetic modifications of DNA and chromatin), and who's evolution in time is governed by simple binding and enzyme kinetics, but that are integrated into networks that can be very complicated.
One really simplified model (inaccurate, but useful) of the computational state and evolution of the cell involves DNA methylation. DNA is methylated to shut it off, demethylation turns it on. To turn some DNA off or on, either DNA methyltransferase (DNMT3a/b) for methylation or one of the Tet proteins for demethylation needs to be guided to that region of DNA, usually through the assembly of some transcription factor complexes. The assembly of these complexes is combinatorial and performs logical addressing depending on the cell state. For example the cell may be expressing TF's A, B, and C, and these guide DNMT3a/b to DNA locus 3xq3945 (made up, whatever) if beta catenin translocates to the nucleus as a response to Wnt signaling, to turn something off. If TF's A, B, and D are expressed, it may bring it to a different location, and may bring Tet there instead, for demethylation.
Anyways, that's an example of "computery" description of cell biology. I don't really like how other responders shot your question down, I think the computer science mindset is really relevant to biology.