4 ms·

Full article https://www.biorxiv.org/content/10.1101/543058v2 https://www.biorxiv.org/content/10.1101/543058v2

• ngold 7y ago
  >Abstract >Understanding information processing in the brain requires us to monitor neural activity in vivo at high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope (2PFM) empowered by all-optical laser scanning, we imaged neural activity in vivo at up to 3,000 frames per second and submicron spatial resolution. This ultrafast imaging method enabled monitoring of both supra- and sub-threshold electrical activity down to 345 μm below the brain surface in head fixed awake mice.>