4 ms·
> For treatment of HIV? For any virus. I didn't say it was safe or effective, I said there is a plausible mechanism of action.
by Alex3917 7y ago
> For treatment of HIV?
For any virus. I didn't say it was safe or effective, I said there is a plausible mechanism of action.
- HarryHirsch 7y agoYou got that wrong. Nitric oxide is a vasodilator, it relaxes smooth muscles in the blood vessels and lungs to increase blood and air flow. It has nothing to do with fighting coronavirus or any other kind of virus, it's supportive treatment so that the patient doesn't suffocate.
- Alex3917 7y ago> It has nothing to do with fighting coronavirus or any other kind of virus, it's supportive treatment so that the patient doesn't suffocate. "Nitric Oxide Inhibits the Replication Cycle of Severe Acute Respiratory Syndrome Coronavirus" https://jvi.asm.org/content/79/3/1966 https://jvi.asm.org/content/79/3/1966 ...
- AstralStorm 7y agoNitric oxide ion in cell is not the same as nitrous oxide gas, typically used for sedation, not taking NO itself. Enhancing NO signaling in cells is hard. The best initial bet there would be using certain class of beta-blockers. (Ones typically used for black patients.) But please do not take unproven drugs with known side effects. The paper is talking about S-nitroso-N-acetylpenicillamine in vitro. This compound is not something anyone wants to actually take.