"we are not talking about some marginal level of efficacy here:" Your above-statement, and then the quote suggests you have no idea how this actually works in

"we are not talking about some marginal level of efficacy here:" Your above-statement, and then the quote suggests you have no idea how this actually works in the real world. The reality is that NO-ONE KNOWS whether there is great efficacy, no efficacy, or marginal efficacy. No one. And we will not until we have a properly designed trial. That link direct us to is horrifyingly badly designed (well, not designed at all). There are all sorts of confounding issues in their results.