3 ms·
The drugs on trial are: 1. Remdesivir (Ebola drug). 2. Chroloquine and Hydroxychroloquine (Malaria drug). 3. Ritonavir/lopinavir (AIDS drug). 4. Ritonavir/l
by ignoramous 7y ago
The drugs on trial are:
1. Remdesivir (Ebola drug).
2. Chroloquine and Hydroxychroloquine (Malaria drug).
3. Ritonavir/lopinavir (AIDS drug).
4. Ritonavir/lopinavir + interferon beta (virus signaling protein).
- jokowueu 7y agoI really thought Camostat mesilate was going to be looked at
- jansan 7y agoI don't even want to know what role lobbyists play in selecting the drugs used for the trial.
- rsynnott 7y agoProbably not a lot. Most of these are out of patent.
- hcknwscommenter 7y agoI guarantee you that Gilead has at least considered filing a patent application on a new use of the old compound. And they will probably get a grant. Same for all the other treatments.
- vikramkr 7y agoClearly if they played a big role they did a terrible job with how many of these drugs are off patent.
- xpuente 7y agoI think it is only approved for treatment in Japan
- HarryHirsch 7y agoBut it has been around for at least 20 years. The safety profile is extremely well known.
- tosser0001 7y agoInteresting to see interferon on here. I remember it being hailed as some sort of wonder drug back in the 80s, but then sort of fell off the radar. https://books.google.com/ngrams/graph?content=interferon https://books.google.com/ngrams/graph?content=interferon
- chasil 7y agoCovid disables the innate immune response by preventing the expression of interferon alpha & beta. This allows it to engage in uncontrolled replication for up to two weeks before the adaptive response brings it under control. This massive viral load greatly contributes to transmission. (Or at least SARS does this.) https://cmr.asm.org/content/20/4/660.long https://cmr.asm.org/content/20/4/660.long
- hcknwscommenter 7y agoThe side effects are awful.